|Toronto East Asylum|
Mary Foster was a patient at the asylum when she began to experience a severe series of headaches. Barclay became infatuated with Foster's genius brain and experimented on her until he killed her. Barclay then had Mary's daughter, Rebecca committed so that he could study her brain in hopes that she would become a genius like her mother ("Epilogue-Barclay").
Dr. Barclay also experimented and killed James Danby at the asylum. When William Murdoch arrested Barclay for the murders it is not known who took his place as asylum administrator ("Epilogue-Barclay").